Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974976 | 0.92 | CCR8 (0.40) | CCR8KDM4ETGFBR1GPR119PKM | |
| SCHEMBL6963513 | 0.92 | GPR119 (0.41) | CCR8KDM4ETGFBR1GPR119PKM | |
| SCHEMBL6975825 | 0.90 | ITGB3 (0.44) | CCR8KDM4ETGFBR1GPR119PKM | |
| SCHEMBL7951214 | 0.89 | TGFBR1 (0.44) | KDM4ETGFBR1GPR119PKMMMP13 | |
| SCHEMBL6969507 | 0.88 | ITGB3 (0.41) | — | |
| SCHEMBL6962633 | 0.87 | MMP13 (0.49) | KDM4ETGFBR1GPR119PKMMMP13 | |
| SCHEMBL6969887 | 0.86 | TGFBR1 (0.49) | TGFBR1MMP13 | |
| SCHEMBL6976329 | 0.86 | F2 (0.44) | ALDH1A1SMN1; SMN2KDM4EHTTTGFBR1 | |
| SCHEMBL7139133 | 0.85 | TGFBR1 (0.42) | TGFBR1MMP13 | |
| SCHEMBL6963135 | 0.85 | STS (0.48) | KDM4ETGFBR1GPR119PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |