Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378230 | 1.00 | GABRR1 (0.34) | GABRR1TGFBR1ALDH1A1FOLH1NAALAD2 | |
| Trifluoroacetic Acid SCHEMBL7661149 | 0.90 | CA1 (0.34) | ALDH1A1CA2CA1MMP2MMP9 | |
| SCHEMBL14215470 | 0.82 | ALDH1A1 (0.35) | TGFBR1ALDH1A1FOLH1NAALAD2GRIA1 | |
| SCHEMBL5514483 | 0.80 | ALDH1A1 (0.52) | ALDH1A1FOLH1CA2CA1MEN1 | |
| SCHEMBL8080233 | 0.78 | ITGB3 (0.36) | GABRR1TGFBR1ALDH1A1FOLH1NAALAD2 | |
| SCHEMBL7248592 | 0.74 | CA1 (0.37) | TGFBR1ALDH1A1CA2CA1MMP2 | |
| Trifluoroacetic Acid SCHEMBL7953714 | 0.73 | CAD (0.33) | CA2CA1CYP2C19 | |
| SCHEMBL8091782 | 0.73 | ITGB3 (0.42) | TGFBR1CA2 | |
| SCHEMBL7298468 | 0.72 | MMP2 (0.60) | ALDH1A1CA2LMNAACEMMP2 | |
| SCHEMBL17323656 | 0.72 | MMP2 (0.60) | ALDH1A1CA2LMNAACEMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| EP-1098878-A1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | LABORATOIRE L. LAFON (FR) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000003986-A1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | disclosed |