Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 8/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 2/20 | 0.39 |
| ▸ | MAX | P61244 | 2/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970078 | 0.89 | MMP13 (0.56) | MMP13MMP1ACKR3KDM4EMAPT | |
| SCHEMBL6962383 | 0.88 | MMP13 (0.41) | MMP13MMP1MYCMAXGPR119 | |
| SCHEMBL7951214 | 0.88 | TGFBR1 (0.44) | MMP13MMP1GPR119TGFBR1KDM4E | |
| SCHEMBL6976329 | 0.88 | F2 (0.44) | MMP13GPR119TGFBR1KDM4E | |
| SCHEMBL6963440 | 0.88 | CYP3A4 (0.41) | MMP13MMP1MYCMAXGPR119 | |
| SCHEMBL6975825 | 0.87 | ITGB3 (0.44) | MMP13MMP1GPR119TGFBR1KDM4E | |
| SCHEMBL6962633 | 0.86 | MMP13 (0.49) | MMP13MMP1GPR119TGFBR1KDM4E | |
| SCHEMBL6978000 | 0.86 | MMP13 (0.56) | MMP13MMP1MYCMAXGPR119 | |
| SCHEMBL6976930 | 0.86 | TGFBR1 (0.45) | MMP13TGFBR1MAPT | |
| SCHEMBL6963135 | 0.85 | STS (0.48) | GPR119TGFBR1KDM4EPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |