Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 2/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 3/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KAT7 | O95251 | 1/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975405 | 0.94 | GPR119 (0.45) | STSGPR119KDM4EPKMYAP1 | |
| SCHEMBL7955983 | 0.93 | YAP1 (0.42) | STSGPR119KDM4EPKMYAP1 | |
| SCHEMBL7951214 | 0.91 | TGFBR1 (0.44) | GPR119KDM4EPKMTGFBR1 | |
| SCHEMBL6962633 | 0.89 | MMP13 (0.49) | GPR119KDM4EPKMITGB3ITGA2B | |
| SCHEMBL6964219 | 0.88 | ITGB3 (0.43) | GPR119KDM4EPKMITGB3ITGA2B | |
| SCHEMBL7955628 | 0.88 | ALDH1A1 (0.42) | STSGPR119KDM4EPKMYAP1 | |
| SCHEMBL6970413 | 0.87 | BCHE (0.47) | GPR119KDM4EPKMYAP1ITGB3 | |
| SCHEMBL6964258 | 0.87 | MMP13 (0.50) | GPR119KDM4EPKMTGFBR1LMNA | |
| SCHEMBL6969634 | 0.87 | ITGB3 (0.37) | GPR119KDM4EPKMITGB3ITGA2B | |
| SCHEMBL6975825 | 0.87 | ITGB3 (0.44) | GPR119KDM4EPKMITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |
| EP-1098878-A1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | LABORATOIRE L. LAFON (FR) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000003986-A1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | disclosed |