SCHEMBL6976864

SCHEMBL6976864

C=CC1(C)OC(=O)NN(C)C1=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL676775 0.71 LMNA (0.54) LMNA
Vinclozolin SCHEMBL8768892 0.58 TSHR (0.46) LMNA
SCHEMBL14275081 0.57 ATAD2 (0.31) LMNA
SCHEMBL2046721 0.57 MMP9 (0.33)
SCHEMBL6927036 0.56
SCHEMBL12948673 0.55
SCHEMBL18043983 0.53
SCHEMBL13116559 0.52
SCHEMBL17589072 0.51 ALDH1A1 (0.31)
SCHEMBL7614661 0.51

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0891341-B1 1,3,4-OXADIAZINE DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AG (DE) 2003-01-02 EP disclosed
US-6414158-B1 INSECTICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 2002-07-02 US disclosed
US-6342599-B1 REACTING SPECIFIED OXADIAZINE DERIVATIVES WITH ALKYLATING OR ACYLATING AGENTS, OR ALDEHYDES OR KETONES, OR THIONYLATING REAGENTS, IN PRESENCE OF DILUENT AND REACTION AUXILIARY IF REQUIRED BAYER AKTIENGESELLSCHAFT (DE) 2002-01-29 US disclosed
CN-1073090-C 1,3,4-oxadiazine derivatives and their use as pesticides BAYER AG (DE) 2001-10-17 CN disclosed
US-6127364-A ANTHELMINTHICS, INSECTICIDES, ACARICIDES, AND NEMATICIDES. BAYER AKTIENGESELLSCHAFT (DE) 2000-10-03 US disclosed
CN-1214683-A 1,3, 4-oxadiazine derivatives and their use as pesticides BAYER AG (DE) 1999-04-21 CN disclosed
EP-0891341-A1 1,3,4-OXADIAZINE DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AG (DE) 1999-01-20 EP disclosed
WO-1997036883-A1 1,3,4-OXADIAZINE DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-10-09 WO disclosed