SCHEMBL676775

SCHEMBL676775

C=CC1(C)OC(=O)N(C)C1=O

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6976864 0.71 LMNA (0.31) LMNA
Trimethadione SCHEMBL28882 0.70 LMNA (1.00) LMNA
Vinclozolin SCHEMBL8768892 0.69 TSHR (0.46) LMNA
Vinclozolin SCHEMBL3862172 0.69 TSHR (0.46) LMNA
SCHEMBL1362309 0.67 LMNA (0.60) LMNA
SCHEMBL23892690 0.61 LMNA (0.52) LMNA
SCHEMBL8363739 0.61 LMNA (0.52) LMNA
SCHEMBL6927036 0.60
SCHEMBL8363757 0.60 LMNA (0.50) LMNA
SCHEMBL8361522 0.60 LMNA (0.50) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9918474-B2 Agents for combating plant pests BAYER INTELLECTUAL PROPERTY GMBH (DE) 2018-03-20 US disclosed
US-20170188582-A1 Agents for Combating Plant Pests BAYER AKTIENGESELLSCHAFT (DE) 2017-07-06 US disclosed
US-8853126-B2 Agents for controlling plant pests BAYER AKTIENGESELLSCHAFT (DE) 2014-10-07 US disclosed
US-20120165374-A1 AGENTS FOR CONTROLLING PLANT PESTS BAYER CROPSCIENCE AG (DE) 2012-06-28 US disclosed
US-20120165374-A1 AGENTS FOR CONTROLLING PLANT PESTS BAYER CROPSCIENCE AG (DE) 2012-06-28 US disclosed
US-8153665-B2 Agents for controlling plant pests BAYER AKTIENGESELLSCHAFT (DE) 2012-04-10 US disclosed
US-8153665-B2 Agents for controlling plant pests BAYER AKTIENGESELLSCHAFT (DE) 2012-04-10 US disclosed
US-7884049-B2 A synergistic mixture of imidacloprid and metalaxyl and does not contain thiram or fludioxonil; pesticides; fungicides; insecticides; plant diseases BAYER CROPSCIENCE AG (DE) 2011-02-08 US disclosed
US-7884049-B2 A synergistic mixture of imidacloprid and metalaxyl and does not contain thiram or fludioxonil; pesticides; fungicides; insecticides; plant diseases BAYER CROPSCIENCE AG (DE) 2011-02-08 US disclosed
US-7868025-B2 Pesticide BAYER CROPSCIENCE AG (DE) 2011-01-11 US disclosed
US-20080108607-A1 Pesticides; fungicides; synergistic BAYER AKTIENGESELLSCHAFT (DE) 2008-05-08 US disclosed
US-7361673-B2 Agents for controlling plant pests BAYER AKTIENGESELLSCHAFT (DE) 2008-04-22 US disclosed
US-20070203208-A1 comprises a mixture of insecticides and fungicides; synergistic BAYER INTELLECTUAL PROPERTY GMBH (DE) 2007-08-30 US disclosed
US-20070203208-A1 comprises a mixture of insecticides and fungicides; synergistic BAYER INTELLECTUAL PROPERTY GMBH (DE) 2007-08-30 US disclosed
US-7232840-B2 Agents for combating plant pests BAYER CROPSCIENCE AG (DE) 2007-06-19 US disclosed
US-7232840-B2 Agents for combating plant pests BAYER CROPSCIENCE AG (DE) 2007-06-19 US disclosed
US-20070043086-A1 synergistic mixture of (2-chloropyridine)-(2-cyanoiminothiazolidine)-methyl and azolo-fingicidal compounds; fungicides, herbicides and insecticide; controlling plant pests ERDELEN CHRISTOPH 2007-02-22 US disclosed
US-20070043086-A1 synergistic mixture of (2-chloropyridine)-(2-cyanoiminothiazolidine)-methyl and azolo-fingicidal compounds; fungicides, herbicides and insecticide; controlling plant pests ERDELEN CHRISTOPH 2007-02-22 US disclosed
US-7179814-B2 Agents for controlling plant pests BAYER AKTIENGESELLSCHAFT (DE) 2007-02-20 US disclosed
US-7179814-B2 Agents for controlling plant pests BAYER AKTIENGESELLSCHAFT (DE) 2007-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165374-A1 AGENTS FOR CONTROLLING PLANT PESTS DDT, ACHE, ERG28 LMNA 4285/4885
US-20070043086-A1 synergistic mixture of (2-chloropyridine)-(2-cyanoiminothiazolidine)-methyl and azolo-fingicidal compounds; fungicides, herbicides and insecticide; controlling plant pests SPHK2, GRM2, DHFR LMNA 3604/4885
US-20070203208-A1 comprises a mixture of insecticides and fungicides; synergistic DDT, CYP51A1, CYP4Z1 LMNA 4109/4885
US-20080108607-A1 Pesticides; fungicides; synergistic DDT, ACHE, CYP4X1 LMNA 4358/4885
US-20170188582-A1 Agents for Combating Plant Pests DDT, CYP51A1, AADAC LMNA 4041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.