Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 11/20 | 0.57 |
| ▸ | HTR7 | P34969 | 6/20 | 0.57 |
| ▸ | HTR2B | P41595 | 6/20 | 0.57 |
| ▸ | HTR2A | P28223 | 4/20 | 0.57 |
| ▸ | HTR1D | P28221 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 6/20 | 0.46 |
| ▸ | HTR3A | P46098 | 5/20 | 0.46 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975733 | 0.83 | HTR4 (0.48) | HTR4HTR7HTR2BHTR2AHTR1D | |
| SCHEMBL6977618 | 0.82 | HTR4 (0.46) | HTR4HTR7HTR2BHTR2AHTR1D | |
| SCHEMBL6973562 | 0.82 | HTR4 (0.46) | HTR4HTR7HTR2BHTR2AHTR1D | |
| SCHEMBL6978353 | 0.80 | ADRB3 (0.46) | HTR4HTR7HTR2BHTR2AHTR1D | |
| SCHEMBL6628061 | 0.79 | HTR1A (0.54) | HTR4HTR7HTR2BHTR2AHTR1D | |
| SCHEMBL6974309 | 0.79 | CCR8 (0.57) | HTR4HTR1AKCNH2 | |
| SCHEMBL3692453 | 0.78 | HTR1A (0.49) | HTR4HTR7HTR2BHTR2AHTR1D | |
| SCHEMBL348618 | 0.77 | HTR1A (0.57) | HTR1A | |
| SCHEMBL6970302 | 0.77 | ADRA1A (0.48) | HTR1AKCNH2 | |
| SCHEMBL6221872 | 0.76 | CHRM3 (0.58) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051413-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-06-04 | — | — | EP | claimed |