Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6626086 | 0.87 | HTR1A (0.47) | HTR4HTR2AHTR2BHTR1DHTR7 | |
| SCHEMBL6978353 | 0.85 | ADRB3 (0.46) | HTR4HTR2AHTR2BHTR1DHTR7 | |
| SCHEMBL6976945 | 0.82 | HTR4 (0.57) | HTR4HTR2AHTR2BHTR1DHTR7 | |
| SCHEMBL6964644 | 0.80 | SLC2A1 (0.55) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6964635 | 0.80 | SLC2A1 (0.55) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6964639 | 0.80 | SLC2A1 (0.55) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6975733 | 0.79 | HTR4 (0.48) | HTR4HTR2AHTR2BHTR1DHTR7 | |
| SCHEMBL6973562 | 0.78 | HTR4 (0.46) | HTR4HTR2AHTR2BHTR1DHTR7 | |
| SCHEMBL6970302 | 0.75 | ADRA1A (0.48) | HTR1AKCNH2ADRA1BKDM4EALDH1A1 | |
| SCHEMBL6628061 | 0.75 | HTR1A (0.54) | HTR4HTR2AHTR2BHTR1DHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051413-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-06-04 | — | — | EP | claimed |