Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979727 | 0.89 | TSHR (0.40) | TSHRMEN1USP2ALDH1A1HPGD | |
| SCHEMBL6986711 | 0.83 | TSHR (0.45) | TSHRMEN1USP2ALDH1A1HPGD | |
| SCHEMBL6983505 | 0.80 | NR3C1 (0.42) | TSHRMEN1USP2ALDH1A1HPGD | |
| SCHEMBL25014144 | 0.76 | ALDH1A1 (0.45) | TSHRMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL6979364 | 0.75 | ALDH1A1 (0.41) | TSHRMEN1USP2ALDH1A1HPGD | |
| SCHEMBL6986437 | 0.74 | PTGER4 (0.41) | TSHRMEN1USP2ALDH1A1HPGD | |
| SCHEMBL6985490 | 0.74 | ALDH1A1 (0.40) | TSHRMEN1USP2ALDH1A1HPGD | |
| SCHEMBL6980994 | 0.73 | RXRA (0.43) | TSHRMEN1USP2ALDH1A1HPGD | |
| SCHEMBL6977399 | 0.73 | PTGER4 (0.42) | TSHRMEN1USP2ALDH1A1HPGD | |
| SCHEMBL6985248 | 0.73 | MAPT (0.42) | TSHRMEN1USP2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |