Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 2/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980994 | 0.86 | RXRA (0.43) | PTGER4HDAC6ATMMAPTNPC1 | |
| SCHEMBL6978509 | 0.86 | PTGER4 (0.40) | PTGER4HDAC1HDAC8HDAC6ATM | |
| SCHEMBL6977736 | 0.86 | CHRM3 (0.40) | PTGER4ATMMAPTNPC1MAPK1 | |
| SCHEMBL6984462 | 0.85 | ATM (0.41) | PTGER4HDAC1HDAC8HDAC6ATM | |
| SCHEMBL6985381 | 0.85 | MMP1 (0.45) | PTGER4HDAC1HDAC8HDAC6ATM | |
| SCHEMBL6982945 | 0.85 | NR3C1 (0.36) | PTGER4ATMMAPTNPC1MAPK1 | |
| SCHEMBL6986817 | 0.85 | THRB (0.42) | HDAC1HDAC8HDAC6ATMMAPT | |
| SCHEMBL6976287 | 0.84 | NOTUM (0.38) | PTGER4HDAC1HDAC8HDAC6ATM | |
| SCHEMBL6979727 | 0.84 | TSHR (0.40) | PTGER4HDAC1HDAC8HDAC6MAPT | |
| SCHEMBL6985248 | 0.84 | MAPT (0.42) | PTGER4MAPTNPC1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |