Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | FPR1 | P21462 | 2/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7090381 | 0.91 | TP53 (0.38) | RORCKDM1AFPR1FPR2MEP1B | |
| SCHEMBL6984169 | 0.91 | KDM1A (0.38) | RORCKDM1AFPR1FPR2MEP1B | |
| SCHEMBL6979172 | 0.90 | KDM1A (0.41) | KDM1AFPR1FPR2MEP1BALDH1A1 | |
| SCHEMBL6982692 | 0.87 | L3MBTL1 (0.38) | KDM1AMEP1BALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6980097 | 0.86 | KDM1A (0.37) | RORCKDM1AFPR1FPR2MEP1B | |
| SCHEMBL6977074 | 0.84 | KDM1A (0.45) | RORCKDM1APOLBFPR1FPR2 | |
| SCHEMBL6986002 | 0.83 | RXRA (0.45) | RORCKDM1AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6986008 | 0.82 | MEN1 (0.39) | RORCFPR1FPR2ALDH1A1MAPT | |
| SCHEMBL6987632 | 0.81 | ALDH1A1 (0.39) | RORCPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6981595 | 0.80 | LTB4R2 (0.46) | ALDH1A1MAPTSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |