Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.34 |
| ▸ | OXTR | P30559 | 2/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979172 | 0.89 | KDM1A (0.41) | KDM1AALDH1A1TSHRKDM4ENPC1 | |
| SCHEMBL6982692 | 0.88 | L3MBTL1 (0.38) | KDM1AALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL6984169 | 0.88 | KDM1A (0.38) | KDM1ARORCAVPR2OXTRAVPR1A | |
| SCHEMBL7090381 | 0.86 | TP53 (0.38) | KDM1ARORCALDH1A1TSHRKDM4E | |
| SCHEMBL6977076 | 0.86 | RORC (0.41) | KDM1ARORCALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6980094 | 0.85 | KDM1A (0.42) | KDM1ARORCALDH1A1TSHRLMNA | |
| SCHEMBL6986002 | 0.84 | RXRA (0.45) | KDM1ARORCALDH1A1TSHRKDM4E | |
| SCHEMBL6981595 | 0.83 | LTB4R2 (0.46) | AVPR2OXTRAVPR1AALDH1A1TSHR | |
| SCHEMBL6986008 | 0.83 | MEN1 (0.39) | RORCAVPR2OXTRAVPR1AALDH1A1 | |
| SCHEMBL6987632 | 0.81 | ALDH1A1 (0.39) | RORCALDH1A1TSHRLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |