Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 7/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.38 |
| ▸ | TPH1 | P17752 | 4/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599894 | 0.86 | PTPN1 (0.33) | SLC7A5PTPN1KDM4ESIRT2NPC1 | |
| SCHEMBL6967105 | 0.78 | CASP1 (0.50) | ALOX15 | |
| SCHEMBL7228564 | 0.78 | SLC7A5 (0.41) | SLC7A5PTPN1TPH1PTGS1KDM4E | |
| SCHEMBL7542381 | 0.76 | SLC7A5 (0.57) | SLC7A5PTPN1TPH1PTGS1KDM4E | |
| SCHEMBL6977330 | 0.76 | SLC7A5 (0.44) | SLC7A5PTPN1SLC7A11TPH1PTGS1 | |
| SCHEMBL6978547 | 0.76 | ALDH1A1 (0.52) | KDM4ETDP1MAPT | |
| SCHEMBL6973856 | 0.76 | CA12 (0.37) | PTPN1HSD17B10PKMLMNATP53 | |
| Benzofuran SCHEMBL6973046 | 0.74 | CASP1 (0.47) | ALOX15 | |
| SCHEMBL7231340 | 0.73 | CASP1 (0.47) | KDM4EALOX15LMNA | |
| SCHEMBL7230948 | 0.72 | CA12 (0.37) | PTPN1HSD17B10PKMLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133491-B1 | NOVEL BENZOFURANE DERIVATIVES, PREPARATION METHOD, USE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2003-02-19 | — | — | EP | disclosed |