Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 7/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TPH1 | P17752 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690008 | 0.79 | ALDH1A1 (0.52) | KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL7660987 | 0.78 | PTPN1 (0.38) | PTPN1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL6977333 | 0.78 | SLC7A5 (0.44) | SLC7A5PTPN1KDM4ETPH1USP2 | |
| SCHEMBL7542381 | 0.74 | SLC7A5 (0.57) | SLC7A5PTPN1KDM4EMEN1KMT2A | |
| SCHEMBL6977330 | 0.72 | SLC7A5 (0.44) | SLC7A5PTPN1KDM4ETPH1USP2 | |
| SCHEMBL7395992 | 0.71 | PTPN1 (0.39) | PTPN1KDM4EHSD17B10SIRT2 | |
| SCHEMBL7599894 | 0.69 | PTPN1 (0.33) | SLC7A5PTPN1KDM4ESIRT2 | |
| SCHEMBL7395988 | 0.65 | KDM4E (0.46) | PTPN1KDM4EHSD17B10 | |
| SCHEMBL24503003 | 0.64 | CNR2 (0.45) | KDM4EMEN1KMT2A | |
| SCHEMBL7538142 | 0.64 | ALDH1A1 (0.47) | SLC7A5PTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586442-B2 | Benzofurane derivatives, their preparation process, their use as medicaments and the pharmaceutical compositions containing them | CARNIATO DENIS (FR) | 2003-07-01 | — | — | US | disclosed |
| US-6458801-B1 | PHARMACEUTICALLY ACCEPTABLE SALTS AND ITS PRODRUG USEFUL FOR TREATING OSTEOPOROSIS. | AVENTIS PHARMA S.A. (FR) | 2002-10-01 | — | — | US | disclosed |