Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982162 | 0.91 | PTGS2 (0.44) | MAPK14PTGS2ACHEBACE1MAOB | |
| SCHEMBL6981848 | 0.89 | MAPK14 (0.40) | MAPK14PTGS2ESR1ESR2ACHE | |
| SCHEMBL6980093 | 0.87 | PTGS2 (0.43) | MAPK14PTGS2ACHEBACE1MAOB | |
| SCHEMBL6979230 | 0.79 | PTGS2 (0.65) | MAPK14PTGS2MAOBPTGS1 | |
| SCHEMBL6977374 | 0.78 | GABRP (0.41) | MAPK14PTGS2ACHEBACE1 | |
| SCHEMBL6973977 | 0.71 | PTGS2 (0.53) | MAPK14PTGS2PTGS1 | |
| SCHEMBL6976542 | 0.71 | PTGS2 (0.69) | MAPK14PTGS2PTGS1 | |
| SCHEMBL1534675 | 0.71 | MAPK14 (0.47) | MAPK14MAOBPLA2G2APLA2G4A | |
| SCHEMBL6976602 | 0.70 | PTGS2 (0.57) | PTGS2MAOBPTGS1 | |
| Hydrochloric Acid SCHEMBL12273214 | 0.70 | MAPK14 (0.46) | MAPK14MAOBPLA2G2APLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105384-B1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-03-26 | — | — | EP | disclosed |
| US-6340694-B1 | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORPORATION (KR) | 2002-01-22 | — | — | US | disclosed |