Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977769 | 0.96 | ALDH1A1 (0.35) | KCNA5PKMMAPTTHRBPSEN1 | |
| SCHEMBL6977607 | 0.82 | KCNH2 (0.40) | KCNA5MAPTTHRBRXFP1ALDH1A1 | |
| SCHEMBL6975922 | 0.74 | NPC1 (0.43) | KCNA5MAPTTHRBRXFP1ALDH1A1 | |
| SCHEMBL6969751 | 0.72 | SGMS1 (0.47) | PKMALDH1A1KMT2A | |
| SCHEMBL6963364 | 0.68 | MEN1 (0.54) | MAPTTHRBALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7825347 | 0.67 | SMN1; SMN2 (0.45) | KCNA5PKMNAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6969760 | 0.67 | AKR1C3 (0.39) | KCNA5MAPTALDH1A1KMT2A | |
| SCHEMBL6977903 | 0.65 | AR (0.46) | MAPTALDH1A1KMT2A | |
| SCHEMBL6975027 | 0.65 | HTR6 (0.45) | MAPTALDH1A1KMT2APTGS2 | |
| SCHEMBL6975974 | 0.65 | AKR1C3 (0.48) | MAPTKMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | claimed |