Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697587 | 0.83 | KMT2A (0.42) | ALDH1A1NPC1RAB9AKMOKDM4E | |
| SCHEMBL697433 | 0.82 | NPC1 (0.44) | ALDH1A1MAPTNPC1RAB9ATP53 | |
| SCHEMBL697919 | 0.79 | NPC1 (0.44) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL27845585 | 0.73 | KMT2A (0.37) | ALDH1A1NPC1RAB9AKDM4EKMT2A | |
| SCHEMBL697121 | 0.73 | TYK2 (0.43) | MAPTNPC1RAB9ASMPD3KMT2A | |
| SCHEMBL1573101 | 0.73 | TYK2 (0.43) | CYP1A2CYP3A4CYP2D6ALDH1A1MAPT | |
| SCHEMBL696226 | 0.73 | KMT2A (0.41) | ALDH1A1NPC1RAB9AALOX15KDM4E | |
| SCHEMBL6002654 | 0.73 | SMPD3 (0.56) | CYP1A2CYP3A4CYP2D6ALDH1A1MAPT | |
| SCHEMBL697771 | 0.72 | SMPD3 (0.42) | CYP1A2CYP3A4CYP2D6ALDH1A1MAPT | |
| SCHEMBL712135 | 0.71 | NPC1 (0.65) | ALDH1A1NPC1RAB9ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |