Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.35 |
| ▸ | TLK2 | Q86UE8 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573101 | 0.89 | TYK2 (0.43) | TYK2KMT2AADRA2AADRA2CADRA1D | |
| SCHEMBL702086 | 0.82 | KMT2A (0.46) | KMT2AADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL705111 | 0.81 | KMT2A (0.48) | TYK2KMT2AJAK2RAB9ANPC1 | |
| SCHEMBL697273 | 0.77 | KMT2A (0.50) | KMT2AADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL697991 | 0.73 | CYP1A2 (0.41) | KMT2ABRAFHDAC1SMPD3RAB9A | |
| SCHEMBL697561 | 0.73 | KMT2A (0.44) | TYK2KMT2AJAK2RAB9ANPC1 | |
| SCHEMBL697587 | 0.71 | KMT2A (0.42) | KMT2ABRAFHDAC1RAB9ANPC1 | |
| SCHEMBL697919 | 0.70 | NPC1 (0.44) | KMT2ABRAFHDAC1RAB9ANPC1 | |
| SCHEMBL698190 | 0.70 | KMT2A (0.52) | KMT2AADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL696873 | 0.70 | KMT2A (0.55) | KMT2AADRA2AADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |