Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981567 | 0.88 | DRD2 (0.40) | DRD2SLC18A3HTR7CARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL6984760 | 0.87 | DRD2 (0.40) | DRD2SLC18A3HTR7CARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL6985853 | 0.87 | DRD2 (0.40) | DRD2SLC18A3HTR7CARM1PRMT6 | |
| SCHEMBL6974487 | 0.85 | DRD2 (0.38) | DRD2SLC18A3HTR7CARM1PRMT6 | |
| SCHEMBL6985256 | 0.78 | MEN1 (0.39) | HRH1MEN1KMT2A | |
| SCHEMBL6982085 | 0.75 | DRD2 (0.41) | DRD2SLC18A3HTR7CARM1PRMT6 | |
| SCHEMBL6979708 | 0.73 | PRMT6 (0.43) | CARM1PRMT6SIGMAR1 | |
| SCHEMBL6976120 | 0.71 | GAA (0.32) | — | |
| SCHEMBL6981079 | 0.71 | HRH3 (0.40) | SLC18A3CARM1PRMT6CCR5SIGMAR1 | |
| SCHEMBL6983492 | 0.70 | CHRNA7 (0.40) | DRD2HTR7SIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | claimed |
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |