Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981567 | 0.89 | DRD2 (0.40) | MEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL6985853 | 0.88 | DRD2 (0.40) | MEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL6984760 | 0.88 | DRD2 (0.40) | MEN1KMT2ATP53 | |
| SCHEMBL6974487 | 0.78 | DRD2 (0.38) | MEN1KMT2ATP53 | |
| SCHEMBL6977829 | 0.78 | DRD2 (0.38) | MEN1KMT2AHRH1 | |
| SCHEMBL6979708 | 0.77 | PRMT6 (0.43) | — | |
| Hydrochloric Acid SCHEMBL6986246 | 0.75 | ADRA1D (0.46) | ALDH1A1KMT2A | |
| SCHEMBL6982085 | 0.74 | DRD2 (0.41) | MEN1KMT2AHRH1 | |
| SCHEMBL6981079 | 0.74 | HRH3 (0.40) | ACHEHRH3 | |
| SCHEMBL8573871 | 0.74 | LMNA (0.42) | MEN1ALDH1A1KMT2AMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |