Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978045 | 0.86 | ALDH1A1 (0.35) | NR3C1RORCNOTUMYAP1ALDH1A1 | |
| SCHEMBL7959305 | 0.84 | NR3C1 (0.42) | NR3C1POLBRORCTP53PARP1 | |
| SCHEMBL6987763 | 0.83 | NR3C1 (0.47) | NR3C1POLBALDH1A1MAPTHPGD | |
| SCHEMBL6980751 | 0.82 | NOTUM (0.44) | NR3C1TP53NOTUMPARP1ALDH1A1 | |
| SCHEMBL6982684 | 0.82 | KDM1A (0.43) | NR3C1TP53NOTUMPARP1ALDH1A1 | |
| SCHEMBL7958945 | 0.80 | PDK1 (0.41) | NR3C1TP53NOTUMPARP1ALDH1A1 | |
| SCHEMBL7962885 | 0.79 | NR3C1 (0.41) | NR3C1POLBTP53YAP1PARP1 | |
| SCHEMBL6976282 | 0.79 | TP53 (0.44) | NR3C1TP53NOTUMALDH1A1MAPT | |
| SCHEMBL6985993 | 0.78 | NR3C1 (0.46) | NR3C1POLBTP53ALDH1A1MAPT | |
| SCHEMBL6985609 | 0.78 | NOTUM (0.39) | NR3C1TP53NOTUMYAP1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |