Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | USP14 | P54578 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978042 | 0.86 | NR3C1 (0.42) | ALDH1A1LMNAMAPTYAP1L3MBTL1 | |
| SCHEMBL6987767 | 0.83 | TP53 (0.42) | ALDH1A1LMNAL3MBTL1GAANR3C1 | |
| SCHEMBL6982692 | 0.82 | L3MBTL1 (0.38) | ALDH1A1LMNAMAPTYAP1L3MBTL1 | |
| SCHEMBL6980758 | 0.81 | NOTUM (0.42) | ALDH1A1LMNAMAPTL3MBTL1NOTUM | |
| SCHEMBL6986000 | 0.80 | NR3C1 (0.36) | ALDH1A1LMNAMAPTL3MBTL1NOTUM | |
| SCHEMBL6985399 | 0.80 | NOTUM (0.36) | ALDH1A1LMNAMAPTYAP1L3MBTL1 | |
| SCHEMBL6976287 | 0.80 | NOTUM (0.38) | ALDH1A1MAPTYAP1L3MBTL1NOTUM | |
| SCHEMBL6977636 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTGAANPC1 | |
| SCHEMBL6985613 | 0.78 | CCR5 (0.37) | ALDH1A1LMNAMAPTYAP1L3MBTL1 | |
| SCHEMBL6987632 | 0.78 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTRORCNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |