Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986604 | 0.84 | BMP1 (0.30) | — | |
| SCHEMBL6987397 | 0.80 | BMP1 (0.37) | — | |
| SCHEMBL6981387 | 0.74 | MMP1 (0.36) | REN | |
| SCHEMBL6939562 | 0.73 | ADAM17 (0.40) | REN | |
| SCHEMBL6987806 | 0.71 | BCHE (0.37) | REN | |
| SCHEMBL6939989 | 0.71 | BCHE (0.39) | REN | |
| SCHEMBL7815506 | 0.69 | BCHE (0.37) | REN | |
| SCHEMBL7928707 | 0.69 | BCHE (0.37) | REN | |
| SCHEMBL6978345 | 0.69 | — | — | |
| SCHEMBL6943418 | 0.69 | BCHE (0.39) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089964-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-10-29 | — | — | EP | disclosed |
| US-6239151-B1 | TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES, OSTEOARTHRITIS, RESPIRATORY DISEASES, TUMORS, CACHEXIA, CARDIOVASCULAR DISEASES, FEVER, HAEMORRHAGE AND SEPSIS, HYDRAZINE DERIVATIVES, | HOFFMANN-LA ROCHE INC. | 2001-05-29 | — | — | US | disclosed |