Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.39 |
| ▸ | ILK | Q13418 | 2/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976235 | 0.92 | APP (0.44) | F2RL3ILKAPPMAPT | |
| SCHEMBL6973119 | 0.87 | P2RY6 (0.40) | F2RL3ILKPTGS2PTGS1MAPT | |
| SCHEMBL6979548 | 0.82 | F2RL3 (0.42) | F2RL3ILKAHRAPPDYRK1A | |
| SCHEMBL6976148 | 0.80 | ILK (0.38) | F2RL3ILKPTGS2PTGS1MAPT | |
| SCHEMBL6978354 | 0.77 | PTGS2 (0.49) | F2RL3PTGS2PTGS1 | |
| SCHEMBL6981822 | 0.76 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL6982699 | 0.75 | F2RL3 (0.43) | F2RL3ILKAPPPTGER1 | |
| SCHEMBL6981806 | 0.74 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL6976230 | 0.69 | PTGS2 (0.49) | F2RL3APPPTGS2PTGS1 | |
| SCHEMBL8954500 | 0.68 | PTGS2 (0.67) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006114-B1 | PYRAZOLE DERIVATIVES AND COX INHIBITORS CONTAINING THEM | GRELAN PHARMACEUTICAL CO (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-6136831-A | ANTIINFLAMMATORY AGENTS, GASTROINTESTINAL AGENTS, ENZYME INHIBITORS | GRELAN PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-1006114-A1 | PYRAZOLE DERIVATIVES AND COX INHIBITORS CONTAINING THEM | Grelan Pharmaceutical Co., Ltd. (JP) | 2000-06-07 | — | — | EP | disclosed |