Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 2/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ILK | Q13418 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976235 | 0.87 | APP (0.44) | F2RL3MEN1KMT2AILKMAPT | |
| SCHEMBL6978359 | 0.87 | F2RL3 (0.39) | F2RL3PTGS1ILKPTGS2MAPT | |
| SCHEMBL6976148 | 0.84 | ILK (0.38) | F2RL3CASP3SENP8SENP7SENP6 | |
| SCHEMBL6973108 | 0.76 | PTGS2 (0.51) | P2RY6F2RL3NPSR1PTGS1PTGS2 | |
| SCHEMBL6978032 | 0.75 | PTGS2 (0.64) | PTGS1PTGS2 | |
| SCHEMBL6976876 | 0.73 | PTGS2 (0.64) | PTGS1PTGS2 | |
| SCHEMBL6982699 | 0.70 | F2RL3 (0.43) | F2RL3ILK | |
| SCHEMBL8954500 | 0.70 | PTGS2 (0.67) | PTGS1PTGS2 | |
| SCHEMBL6973228 | 0.68 | PTGS2 (0.64) | PTGS1PTGS2 | |
| SCHEMBL4673772 | 0.68 | RAB9A (0.37) | NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006114-B1 | PYRAZOLE DERIVATIVES AND COX INHIBITORS CONTAINING THEM | GRELAN PHARMACEUTICAL CO (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-6136831-A | ANTIINFLAMMATORY AGENTS, GASTROINTESTINAL AGENTS, ENZYME INHIBITORS | GRELAN PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-1006114-A1 | PYRAZOLE DERIVATIVES AND COX INHIBITORS CONTAINING THEM | Grelan Pharmaceutical Co., Ltd. (JP) | 2000-06-07 | — | — | EP | disclosed |