Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.43 |
| ▸ | APP | P05067 | 9/20 | 0.41 |
| ▸ | ILK | Q13418 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979548 | 0.93 | F2RL3 (0.42) | F2RL3APPILKLDHAPTGER1 | |
| SCHEMBL6976235 | 0.81 | APP (0.44) | F2RL3APPILKMAOBCCNE1 | |
| SCHEMBL6982685 | 0.77 | F2RL3 (0.49) | F2RL3APPILKMAOBCCNE1 | |
| SCHEMBL6978359 | 0.75 | F2RL3 (0.39) | F2RL3APPILKPTGER1 | |
| SCHEMBL6973119 | 0.70 | P2RY6 (0.40) | F2RL3ILK | |
| SCHEMBL6979539 | 0.69 | F2RL3 (0.48) | F2RL3ILKLDHA | |
| SCHEMBL15425178 | 0.65 | APP (0.82) | APPILKMAOB | |
| SCHEMBL16708071 | 0.64 | F2RL3 (0.76) | F2RL3 | |
| SCHEMBL2137760 | 0.62 | APP (0.67) | APPILKMAOB | |
| SCHEMBL6976148 | 0.62 | ILK (0.38) | F2RL3ILK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006114-B1 | PYRAZOLE DERIVATIVES AND COX INHIBITORS CONTAINING THEM | GRELAN PHARMACEUTICAL CO (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-6136831-A | ANTIINFLAMMATORY AGENTS, GASTROINTESTINAL AGENTS, ENZYME INHIBITORS | GRELAN PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-1006114-A1 | PYRAZOLE DERIVATIVES AND COX INHIBITORS CONTAINING THEM | Grelan Pharmaceutical Co., Ltd. (JP) | 2000-06-07 | — | — | EP | disclosed |