Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 7/20 | 0.42 |
| ▸ | ILK | Q13418 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 2/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982699 | 0.93 | F2RL3 (0.43) | F2RL3ILKLDHAPTGER1APP | |
| SCHEMBL6978359 | 0.82 | F2RL3 (0.39) | F2RL3ILKDYRK1AAHRPTGER1 | |
| SCHEMBL6979539 | 0.77 | F2RL3 (0.48) | F2RL3ILKDYRK1AAHRLDHA | |
| SCHEMBL6976235 | 0.74 | APP (0.44) | F2RL3ILKAPPKDM4EALDH1A1 | |
| SCHEMBL6982685 | 0.69 | F2RL3 (0.49) | F2RL3ILKAPP | |
| SCHEMBL6973119 | 0.69 | P2RY6 (0.40) | F2RL3ILKMEN1KMT2A | |
| SCHEMBL10706363 | 0.66 | APP (0.68) | ILKDYRK1AAHRAPPKDM4E | |
| SCHEMBL16708103 | 0.63 | F2RL3 (0.75) | F2RL3KDM4EMEN1KMT2A | |
| SCHEMBL6976148 | 0.62 | ILK (0.38) | F2RL3ILKKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL1319670 | 0.61 | SMN1; SMN2 (0.57) | ILKDYRK1AAHRALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006114-B1 | PYRAZOLE DERIVATIVES AND COX INHIBITORS CONTAINING THEM | GRELAN PHARMACEUTICAL CO (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-6136831-A | ANTIINFLAMMATORY AGENTS, GASTROINTESTINAL AGENTS, ENZYME INHIBITORS | GRELAN PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-1006114-A1 | PYRAZOLE DERIVATIVES AND COX INHIBITORS CONTAINING THEM | Grelan Pharmaceutical Co., Ltd. (JP) | 2000-06-07 | — | — | EP | disclosed |