Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.43 |
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
| ▸ | CNR1 | P21554 | 5/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | BCL2 | P10415 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977942 | 0.92 | CNR2 (0.44) | CNR2ACHECNR1MAPTKDM4E | |
| SCHEMBL6970142 | 0.79 | CNR2 (0.54) | CNR2ACHECNR1MAPTHPGD | |
| SCHEMBL6973555 | 0.76 | ACHE (0.48) | CNR2ACHECNR1MAPTKDM4E | |
| SCHEMBL6968101 | 0.75 | CNR2 (0.48) | CNR2ACHECNR1MAPTKDM4E | |
| SCHEMBL6975193 | 0.74 | CNR2 (0.51) | CNR2ACHECNR1MAPTHPGD | |
| SCHEMBL6973625 | 0.72 | ALDH1A1 (0.51) | CNR2ACHECNR1MAPTHPGD | |
| SCHEMBL6970884 | 0.71 | CNR2 (0.54) | CNR2ACHECNR1 | |
| SCHEMBL6967696 | 0.70 | ACHE (0.44) | CNR2ACHECNR1MAPTALDH1A1 | |
| SCHEMBL6975356 | 0.69 | LMNA (0.45) | MAPTKDM4EALDH1A1PTGS2 | |
| SCHEMBL6973989 | 0.69 | CNR2 (0.55) | CNR2ACHECNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | claimed |