Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972305 | 0.89 | FPR3 (0.44) | TAAR1EPHX1EPHX2OPRD1OPRK1 | |
| SCHEMBL6971593 | 0.88 | ADRA1A (0.40) | ADRA1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL6967337 | 0.87 | OPRD1 (0.39) | ADRA1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL6980217 | 0.86 | ACHE (0.43) | ADRA1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL6973626 | 0.86 | OPRD1 (0.40) | ADRA1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL6971228 | 0.85 | ADRA1A (0.44) | ADRA1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL6969075 | 0.85 | OPRD1 (0.38) | ADRA1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL6969796 | 0.84 | OPRD1 (0.42) | OPRD1OPRK1OPRL1ALDH1A1LMNA | |
| SCHEMBL6979637 | 0.83 | ALDH1A1 (0.40) | OPRD1OPRK1OPRL1ALDH1A1LMNA | |
| SCHEMBL6978058 | 0.83 | ADRA1A (0.46) | ADRA1AADRA2AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202984-B1 | DIPHENYL-PIPERIDINE DERIVATE | ASTRAZENECA UK LTD (GB) | 2003-03-05 | — | — | EP | claimed |