Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6980238 | 0.99 | ALDH1A1 (0.40) | MEN1KMT2AATMEGFRALDH1A1 | |
| SCHEMBL8309041 | 0.90 | HTR2A (0.41) | MEN1KMT2AATMEGFRALDH1A1 | |
| SCHEMBL6985836 | 0.85 | DRD2 (0.40) | MEN1KMT2AALDH1A1HTR2CHTR2B | |
| SCHEMBL6980360 | 0.85 | SLC18A3 (0.40) | HTTHTR7DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL6980227 | 0.84 | DRD2 (0.40) | MEN1KMT2AALDH1A1HTR2CHTR2B | |
| SCHEMBL4035933 | 0.82 | ALOX15 (0.50) | MEN1KMT2AALDH1A1HTR2CHTR2B | |
| SCHEMBL6982775 | 0.81 | SLC6A3 (0.37) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL6983488 | 0.80 | DRD2 (0.41) | MEN1KMT2AALDH1A1HTR2CHTR2B | |
| SCHEMBL8309047 | 0.80 | ALDH1A1 (0.38) | MEN1KMT2AATMALDH1A1KDM4E | |
| SCHEMBL8713491 | 0.77 | ALOX5 (0.38) | MEN1KMT2AALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |