Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985412 | 0.95 | — | — | |
| Oxalic Acid SCHEMBL6980644 | 0.83 | GRM5 (0.42) | HRH1CHRM3 | |
| SCHEMBL6980205 | 0.78 | CARM1 (0.43) | — | |
| Oxalic Acid SCHEMBL6977629 | 0.78 | SLC6A4 (0.39) | — | |
| SCHEMBL6983930 | 0.78 | CHRM2 (0.43) | HRH1CHRM3 | |
| Oxalic Acid SCHEMBL6985362 | 0.77 | BCHE (0.40) | — | |
| SCHEMBL6981562 | 0.77 | DRD2 (0.43) | — | |
| SCHEMBL6981384 | 0.77 | DRD2 (0.43) | — | |
| SCHEMBL7811043 | 0.77 | DRD2 (0.43) | — | |
| Oxalic Acid SCHEMBL6984815 | 0.77 | SLC6A4 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |