Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUND | P17535 | 1/20 | 0.46 |
| ▸ | FOSB | P53539 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974797 | 0.80 | ACHE (0.48) | HTR6BCHEACHEGRIN1GRIN2A | |
| SCHEMBL3569881 | 0.79 | MAPK7 (0.53) | JUNDFOSBHTR2CHTR6MEN1 | |
| SCHEMBL6975725 | 0.76 | NUDT1 (0.53) | HTR2CHTR6BCHEACHEMEN1 | |
| SCHEMBL6977642 | 0.76 | MAPK7 (0.57) | ACHEMEN1KMT2AALDH1A1 | |
| SCHEMBL23009237 | 0.74 | KDM4E (0.59) | MEN1KMT2AKDM4EHTTAPP | |
| SCHEMBL7716402 | 0.73 | KDM4E (0.58) | HTR2CHTR6KDM4EHSD17B10 | |
| SCHEMBL6978719 | 0.73 | MEN1 (0.49) | JUNDFOSBHTR2CMEN1KMT2A | |
| SCHEMBL15650495 | 0.72 | PIM3 (0.44) | BCHEACHECHRM1GRIN1GRIN2A | |
| SCHEMBL3570195 | 0.71 | MAPK7 (0.53) | JUNDFOSBHTR2CHTR6MEN1 | |
| SCHEMBL11236323 | 0.71 | HTR2C (0.47) | JUNDFOSBHTR2CHTR6ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892795-B1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMA (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5948786-A | BLOCKING TUMOR NECROSIS FACTOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-09-07 | — | — | US | disclosed |