Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 5/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 4/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4872685 | 0.93 | PTGS2 (0.33) | ADAMTS5PTGS2PTGS1CCR2PLA2G2A | |
| SCHEMBL4874189 | 0.92 | PTGS2 (0.33) | ADAMTS5PTGS2PTGS1CCR2PLA2G2A | |
| SCHEMBL4866765 | 0.91 | LMNA (0.38) | ADAMTS5CCR2PLA2G2AHRH3ALDH1A1 | |
| SCHEMBL4875402 | 0.91 | PLA2G2A (0.32) | ADAMTS5PTGS2PTGS1CCR2PLA2G2A | |
| SCHEMBL4875263 | 0.91 | PLA2G2A (0.34) | ADAMTS5PTGS2CCR2PLA2G2AHRH3 | |
| SCHEMBL4866661 | 0.91 | GPR119 (0.33) | ADAMTS5PTGS2CCR2PLA2G2AHRH3 | |
| SCHEMBL4870404 | 0.91 | EPHX2 (0.34) | ADAMTS5PTGS2CCR2PLA2G2AHRH3 | |
| SCHEMBL4869982 | 0.90 | ADAMTS5 (0.37) | ADAMTS5CCR2HRH3CCR5RORC | |
| SCHEMBL4876934 | 0.90 | PLA2G2A (0.32) | ADAMTS5PTGS2CCR2PLA2G2ARORC | |
| SCHEMBL4870412 | 0.89 | NPSR1 (0.35) | ADAMTS5PTGS2ALDH1A1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289965-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090081-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-29 | — | — | WO | disclosed |