Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6985271 | 0.99 | CYP11B2 (0.50) | CYP11B2CYP11B1CYP17A1CYP19A1KDM4E | |
| SCHEMBL6982148 | 0.91 | CYP11B2 (0.52) | CYP11B2CYP11B1CYP17A1CYP19A1KDM4E | |
| SCHEMBL6981655 | 0.90 | KDM4E (0.55) | CYP11B2CYP11B1CYP17A1CYP19A1KDM4E | |
| Hydrochloric Acid SCHEMBL6982572 | 0.89 | KDM4E (0.54) | CYP11B2CYP11B1CYP17A1CYP19A1KDM4E | |
| SCHEMBL6983025 | 0.88 | KDM4E (0.49) | CYP11B2CYP11B1CYP17A1CYP19A1KDM4E | |
| Hydrochloric Acid SCHEMBL6986512 | 0.87 | KDM4E (0.48) | CYP11B2CYP11B1CYP17A1CYP19A1KDM4E | |
| SCHEMBL6985509 | 0.87 | MKNK1 (0.46) | CYP11B2CYP11B1CYP19A1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL6979381 | 0.86 | MKNK1 (0.45) | CYP11B2CYP11B1CYP19A1ALDH1A1HPGD | |
| SCHEMBL6985848 | 0.86 | DYRK1A (0.50) | CYP11B2CYP11B1CYP17A1CYP19A1ALDH1A1 | |
| SCHEMBL6982439 | 0.85 | SMN1; SMN2 (0.53) | CYP11B2CYP11B1CYP17A1CYP19A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | DAIICHI PHARMACEUTICAL CO. LTD. | 2003-07-10 | — | — | US | disclosed |
| EP-1283209-A1 | NOVEL BENZOTHIOPHENE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | CYP17A1, CYP21A2, HSD17B1 | CYP11B2 18/4885CYP11B1 8/4885CYP17A1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.