Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982148 | 0.86 | CYP11B2 (0.52) | SMN1; SMN2HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6985848 | 0.86 | DYRK1A (0.50) | ALDH1A1MKNK1MKNK2CYP19A1CYP11B1 | |
| SCHEMBL6982299 | 0.85 | CYP11B2 (0.51) | SMN1; SMN2HPGDALDH1A1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL6985271 | 0.84 | CYP11B2 (0.50) | SMN1; SMN2HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6985095 | 0.83 | CYP11B1 (0.45) | HPGDALDH1A1KDM4EMKNK1MKNK2 | |
| SCHEMBL6981655 | 0.82 | KDM4E (0.55) | SMN1; SMN2HPGDALDH1A1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL6985047 | 0.82 | CYP11B1 (0.44) | HPGDALDH1A1KDM4EMKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL6982572 | 0.81 | KDM4E (0.54) | SMN1; SMN2HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6985680 | 0.81 | CYP19A1 (0.50) | ALDH1A1KDM4EMAPK1CYP19A1CYP11B1 | |
| SCHEMBL11342031 | 0.80 | KDM4E (0.70) | SMN1; SMN2KDM4EMAPK1HSD17B10MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | DAIICHI PHARMACEUTICAL CO. LTD. | 2003-07-10 | — | — | US | disclosed |
| EP-1283209-A1 | NOVEL BENZOTHIOPHENE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | CYP17A1, CYP21A2, HSD17B1 | SMN1; SMN2 4812/4885HPGD 884/4885ALDH1A1 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.