Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6979381 | 0.99 | MKNK1 (0.45) | MKNK1MKNK2RXRARXRBGABRA1 | |
| SCHEMBL6984794 | 0.91 | MKNK1 (0.44) | MKNK1MKNK2IRAK4KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL6985178 | 0.90 | MKNK1 (0.43) | MKNK1MKNK2IRAK4KMT2ARAB9A | |
| SCHEMBL6982299 | 0.87 | CYP11B2 (0.51) | IRAK4KMT2ARAB9AMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL6985271 | 0.86 | CYP11B2 (0.50) | IRAK4KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL6985848 | 0.83 | DYRK1A (0.50) | MKNK1MKNK2PIK3CAPIK3CGPIK3CD | |
| SCHEMBL6982148 | 0.81 | CYP11B2 (0.52) | GABRA1GABRG2GABRB3GABRA3IRAK4 | |
| SCHEMBL6985095 | 0.80 | CYP11B1 (0.45) | MKNK1MKNK2PIK3CAPIK3CDPIP5K1C | |
| SCHEMBL6986226 | 0.80 | FLT3 (0.47) | KMT2ARAB9AMEN1NPC1DYRK1A | |
| SCHEMBL6981139 | 0.79 | CYP3A4 (0.54) | PIK3CAPIK3CGPIK3CDPIK3CBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | DAIICHI PHARMACEUTICAL CO. LTD. | 2003-07-10 | — | — | US | disclosed |
| EP-1283209-A1 | NOVEL BENZOTHIOPHENE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | CYP17A1, CYP21A2, HSD17B1 | MKNK1 3971/4885MKNK2 4113/4885RXRA 3672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.