SCHEMBL6986068

SCHEMBL6986068

Cc1c(OC(=O)O)ccc2snnc12

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 13/20 0.43
ALDH1A1 P00352 1/20 0.38
THRB P10828 2/20 0.34
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10589330 0.78 MAPT (0.38) MAPTALDH1A1LMNAPOLBNPC1
SCHEMBL6986066 0.76 THRB (0.36) MAPTALDH1A1THRBLMNAPOLB
SCHEMBL6982304 0.75 KDM4E (0.39) MAPTNPC1RAB9A
SCHEMBL6984168 0.73 ALDH1A1 (0.44) MAPTALDH1A1LMNAPOLBNPC1
SCHEMBL10589746 0.72 BAZ1A (0.36) MAPTALDH1A1THRBLMNAPOLB
SCHEMBL6979296 0.71 MAPT (0.46) MAPTALDH1A1LMNANPC1RAB9A
SCHEMBL7478899 0.69 MAPT (0.37) MAPT
SCHEMBL10589364 0.69 MAPT (0.43) MAPTALDH1A1THRBPOLBNPC1
SCHEMBL983662 0.66 PTPN1 (0.45) MAPTALDH1A1LMNAPOLBRAB9A
SCHEMBL28061093 0.66 MAPT (0.44) MAPTALDH1A1LMNAPOLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1177194-B1 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS BASF AG (DE) 2003-09-17 EP disclosed
EP-1177194-A1 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS BASF AKTIENGESELLSCHAFT (DE) 2002-02-06 EP disclosed
WO-2000068228-A1 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS BASF AKTIENGESELLSCHAFT (DE) 2000-11-16 WO disclosed