Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.54 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | P4HB | P07237 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830265 | 0.89 | KCNN4 (0.47) | KCNN4KCNA5FFAR1GFERMAOB | |
| SCHEMBL7056650 | 0.85 | KCNN4 (0.45) | KCNN4KCNA5FFAR1GFERMAOB | |
| SCHEMBL8377344 | 0.82 | RORC (0.44) | MAOB | |
| SCHEMBL8120082 | 0.82 | FFAR1 (0.45) | KCNN4KCNA5FFAR1GFERMAOB | |
| SCHEMBL6982511 | 0.81 | CRHBP (0.52) | KCNN4KCNA5FFAR1MAOBFFAR4 | |
| SCHEMBL8106455 | 0.80 | KCNN4 (0.43) | KCNN4KCNA5FFAR1GFERMAOB | |
| SCHEMBL7057421 | 0.80 | FFAR1 (0.47) | KCNN4KCNA5FFAR1MAOBFFAR4 | |
| SCHEMBL8117060 | 0.80 | FFAR1 (0.42) | KCNN4KCNA5FFAR1MAOBFFAR4 | |
| SCHEMBL430658 | 0.78 | TP53 (0.49) | — | |
| SCHEMBL7357492 | 0.78 | FFAR1 (0.47) | KCNN4KCNA5FFAR1MAOBFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030166694-A1 | Glycinamides | MERCK PATENT GMBH (DE) | 2003-09-04 | — | — | US | disclosed |
| EP-1284961-A1 | GLYCINAMIDES | MERCK PATENT GmbH (DE) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001092219-A1 | GLYCINAMIDES | MERCK PATENT GMBH (DE) | 2001-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166694-A1 | Glycinamides | F11, SERPINC1, F13A1 | KCNN4 4233/4885KCNA5 3355/4885FFAR1 906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.