Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9036977 | 0.86 | MCL1 (0.35) | — | |
| SCHEMBL6327672 | 0.81 | TRPA1 (0.36) | LMNA | |
| SCHEMBL9904854 | 0.70 | LMNA (0.33) | LMNA | |
| SCHEMBL3525771 | 0.67 | TRPA1 (0.31) | PIM1 | |
| SCHEMBL9680591 | 0.64 | TRPA1 (0.32) | — | |
| SCHEMBL14067698 | 0.64 | NOTUM (0.42) | PARP1 | |
| SCHEMBL6667856 | 0.63 | TRPA1 (0.36) | — | |
| SCHEMBL9275405 | 0.59 | PARP1 (0.44) | PARP1 | |
| SCHEMBL30082247 | 0.59 | PARP1 (0.44) | PARP1 | |
| SCHEMBL2860722 | 0.59 | MAOA (0.49) | PARP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299386-A1 | PYRROLOQUINOLONES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-04-09 | — | — | EP | claimed |
| WO-2002002558-A1 | PYRROLOQUINOLONES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-01-10 | — | — | WO | claimed |
| EP-1299386-A1 | PYRROLOQUINOLONES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-04-09 | — | — | EP | disclosed |
| WO-2002002558-A1 | PYRROLOQUINOLONES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-01-10 | — | — | WO | disclosed |