Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CD69 | Q07108 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982539 | 0.86 | PARP1 (0.36) | — | |
| SCHEMBL6327672 | 0.82 | TRPA1 (0.36) | MEN1KMT2A | |
| SCHEMBL11400593 | 0.73 | FGFR1 (0.35) | CD69HTR1AMEN1KMT2A | |
| SCHEMBL11202182 | 0.64 | NOTUM (0.39) | MCL1HTR1AMEN1KMT2A | |
| SCHEMBL1650892 | 0.63 | MAOA (0.35) | — | |
| Hydrochloric Acid SCHEMBL10432400 | 0.62 | NOTUM (0.38) | MCL1MEN1KMT2A | |
| SCHEMBL11832728 | 0.62 | NOTUM (0.41) | MEN1KMT2A | |
| SCHEMBL2476392 | 0.62 | TSHR (0.44) | MCL1CD69MEN1KMT2A | |
| SCHEMBL27637416 | 0.62 | NOTUM (0.40) | MEN1KMT2A | |
| SCHEMBL4767870 | 0.62 | NOTUM (0.44) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390135-B1 | Pyrroloquinoline derivatives, antimicrobial agents using the same and process for preparing the same | OTSUKA PHARMA CO LTD (JP) | 1996-06-05 | — | — | EP | disclosed |
| EP-0390135-A1 | Pyrroloquinoline derivatives, antimicrobial agents using the same and process for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-03 | — | — | EP | disclosed |
| US-4603199-A | Phenyl-substituted tricyclic antibacterial agent intermediates | RIKER LABORATORIES, INC. (US) | 1986-07-29 | — | — | US | disclosed |
| EP-0107201-A2 | Phenyl-substituted tricyclic antibacterial agents | RIKER LABORATORIES, INCORPORATED (US) | 1984-05-02 | — | — | EP | disclosed |
| US-4443447-A | Phenyl-substituted tricyclic antibacterial agents | RIKER LABORATORIES, INC. (US) | 1984-04-17 | — | — | US | disclosed |