Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 17/20 | 0.45 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984730 | 0.92 | UTS2R (0.44) | UTS2RMBTPS1 | |
| SCHEMBL6983023 | 0.85 | UTS2R (0.45) | UTS2RMBTPS1SLC6A2SLC6A4 | |
| SCHEMBL7143855 | 0.80 | SLC6A2 (0.40) | UTS2RSLC6A2SLC6A4KCNH2 | |
| SCHEMBL7140946 | 0.79 | SLC6A2 (0.40) | UTS2RSLC6A2SLC6A4KCNH2 | |
| SCHEMBL6984733 | 0.77 | UTS2R (0.46) | UTS2RMBTPS1SLC6A2SLC6A4 | |
| SCHEMBL6594029 | 0.76 | UTS2R (0.55) | UTS2R | |
| SCHEMBL6599108 | 0.73 | MAPK1 (0.39) | UTS2RSLC6A2SLC6A4KCNH2 | |
| SCHEMBL6981910 | 0.72 | REN (0.42) | UTS2RSLC6A2SLC6A4KCNH2 | |
| SCHEMBL6981109 | 0.70 | REN (0.42) | MBTPS1SLC6A2SLC6A4KCNH2 | |
| SCHEMBL6980413 | 0.69 | HRH3 (0.40) | MBTPS1SLC6A2SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246619-A4 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-05-02 | — | — | EP | claimed |
| EP-1246619-A1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-09 | — | — | EP | claimed |
| WO-2001045700-A1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-06-28 | — | — | WO | claimed |
| EP-1246619-A4 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| EP-1246619-A1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001045700-A1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-06-28 | — | — | WO | disclosed |