Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 15/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984733 | 0.92 | UTS2R (0.46) | UTS2ROPRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6983020 | 0.85 | UTS2R (0.45) | UTS2RSLC6A2SLC6A4MBTPS1 | |
| SCHEMBL7143857 | 0.79 | SLC6A2 (0.43) | UTS2RSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6979203 | 0.78 | SLC6A2 (0.43) | UTS2RSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6984730 | 0.77 | UTS2R (0.44) | UTS2RMBTPS1 | |
| SCHEMBL6599112 | 0.72 | MAPK1 (0.42) | UTS2RSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6981912 | 0.70 | REN (0.44) | UTS2RSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6981110 | 0.69 | REN (0.44) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6980416 | 0.68 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3MBTPS1 | |
| SCHEMBL6985986 | 0.67 | MBTPS1 (0.44) | SLC6A2SLC6A4SLC6A3MBTPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246619-A4 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-05-02 | — | — | EP | claimed |
| EP-1246619-A1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-09 | — | — | EP | claimed |
| WO-2001045700-A1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-06-28 | — | — | WO | claimed |
| EP-1246619-A4 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| EP-1246619-A1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001045700-A1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-06-28 | — | — | WO | disclosed |