Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 5/20 | 0.33 |
| ▸ | PRKACG | P22612 | 5/20 | 0.33 |
| ▸ | PRKACB | P22694 | 5/20 | 0.33 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.32 |
| ▸ | CDK9 | P50750 | 3/20 | 0.32 |
| ▸ | CDK4 | P11802 | 3/20 | 0.32 |
| ▸ | CCND1 | P24385 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6983051 | 0.81 | CAMK2D (0.46) | PRKACAPRKACGPRKACBCAMK2DRPS6KB1 | |
| SCHEMBL6976738 | 0.79 | RPS6KB1 (0.32) | PRKACAPRKACGPRKACBCAMK2DRPS6KB1 | |
| Trifluoroacetic Acid SCHEMBL7011017 | 0.78 | CAMK2D (0.54) | PRKACAPRKACGPRKACBCAMK2DRPS6KB1 | |
| Trifluoroacetic Acid SCHEMBL7006503 | 0.74 | TPSAB1 (0.43) | PRKACAPRKACGPRKACBCAMK2DRPS6KB1 | |
| Acetic Acid SCHEMBL7014928 | 0.72 | PRKCB (0.54) | PRKACAPRKACGPRKACBCAMK2DRPS6KB1 | |
| SCHEMBL7005539 | 0.70 | CDK4 (0.55) | PRKACAPRKACGPRKACBCAMK2DRPS6KB1 | |
| SCHEMBL7005333 | 0.70 | PRKCB (0.56) | PRKACAPRKACGPRKACBCAMK2DRPS6KB1 | |
| SCHEMBL7007889 | 0.68 | CAMK2D (0.62) | PRKACAPRKACGPRKACBCAMK2DRPS6KB1 | |
| SCHEMBL7009039 | 0.68 | PRKACA (0.62) | PRKACAPRKACGPRKACBCAMK2DRPS6KB1 | |
| Acetic Acid SCHEMBL7007595 | 0.68 | PRKCA (0.59) | PRKACAPRKACGPRKACBCAMK2DRPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095039-B1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-08-27 | — | — | EP | disclosed |
| US-6346625-B1 | ENZYME INHIBITORS FOR PROTEIN KINASES | ASTRAZENECA AB (SE) | 2002-02-12 | — | — | US | disclosed |