Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6399537 | 1.00 | MEN1 (0.46) | MEN1KMT2APDGFRBPDGFRAMGAM | |
| SCHEMBL6982024 | 0.87 | FAAH (0.44) | MEN1KMT2APDGFRBPDGFRAALDH1A1 | |
| SCHEMBL6403012 | 0.87 | FAAH (0.44) | MEN1KMT2APDGFRBPDGFRAALDH1A1 | |
| SCHEMBL6400707 | 0.81 | DYRK3 (0.31) | MEN1KMT2AMAPT | |
| SCHEMBL6405033 | 0.80 | MASP2 (0.36) | MEN1KMT2AALDH1A1MAPTPKM | |
| SCHEMBL6400559 | 0.76 | MEN1 (0.41) | MEN1KMT2APDGFRBPDGFRAMGAM | |
| SCHEMBL10673413 | 0.74 | CYP1A2 (0.50) | PDGFRBPDGFRAMGAMALDH1A1KDM1A | |
| SCHEMBL28361265 | 0.74 | MEN1 (0.51) | MEN1KMT2APDGFRBPDGFRAMGAM | |
| SCHEMBL4664285 | 0.73 | KDM1A (0.47) | MEN1KMT2APDGFRBPDGFRAMGAM | |
| SCHEMBL701411 | 0.72 | ALDH1A1 (0.53) | KMT2APDGFRBPDGFRAMGAMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090100-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-11-29 | — | — | WO | disclosed |