Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Trifluoromethanesulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL28168879 | 0.96 | CA5A (0.46) | CA5ACA5BALDH1A1L3MBTL1CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL28128156 | 0.96 | CA5A (0.46) | CA5ACA5BALDH1A1L3MBTL1CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL28101503 | 0.96 | CA5A (0.46) | CA5ACA5BALDH1A1L3MBTL1CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL6288325 | 0.96 | CA5A (0.46) | CA5ACA5BALDH1A1L3MBTL1CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL15544820 | 0.96 | CA5A (0.46) | CA5ACA5BALDH1A1L3MBTL1CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL295 | 0.96 | — | — | |
| Trifluoromethanesulfonic Acid SCHEMBL39465 | 0.96 | ALDH1A1 (0.50) | CA5ACA5BALDH1A1L3MBTL1CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL3507077 | 0.96 | — | — | |
| Trifluoromethanesulfonic Acid SCHEMBL3950101 | 0.96 | — | — | |
| Trifluoromethanesulfonic Acid SCHEMBL25293989 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239467-A | Asphalt-based hard carbon material for negative electrode of sodium ion battery and preparation method thereof | 湖南碳导新材料科技有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-107974280-A | A kind of liquid acid alkylation reaction method | 中国石油化工股份有限公司 | 2018-05-01 | — | — | CN | claimed |
| EP-1292269-A1 | AGENT FOR DYEING KERATIN CONTAINING FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-03-19 | — | — | EP | claimed |
| WO-2001097765-A1 | AGENT FOR DYEING KERATIN CONTAINING FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-12-27 | — | — | WO | claimed |
| EP-0295050-B1 | PROCESS FOR PREPARING A 4,4-DIPHENYLBUTANOIC ACID DERIVATIVE | PFIZER INC. (US) | 1991-04-17 | — | — | EP | claimed |
| EP-0295050-A1 | Process for preparing a 4,4-diphenylbutanoic acid derivative | PFIZER INC. (US) | 1988-12-14 | — | — | EP | claimed |
| EP-3744756-B1 | ACETOXY SYSTEMS | EVONIK OPERATIONS GMBH (DE) | 2024-07-03 | — | — | EP | disclosed |
| CN-112011054-B | Acetoxygen systems | 赢创运营有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-114057182-B | Method for dispersing nano material | 中国科学院苏州纳米技术与纳米仿生研究所 | 2023-08-18 | — | — | CN | disclosed |
| CN-110139644-B | Compositions and methods for treating insulin resistance | 坦普尔大学 | 2023-05-23 | — | — | CN | disclosed |
| US-11596615-B2 | Compositions and methods for treatment of insulin resistance | Temple University—Of the Commonwealth System of Higher Education (US) | 2023-03-07 | — | — | US | disclosed |
| CN-114369045-B | Fluorine-containing alkylthio substituted olefin derivative and synthesis method thereof | 中国科学院大连化学物理研究所 | 2022-10-21 | — | — | CN | disclosed |
| CN-114057182-A | Method for dispersing nano material | 中国科学院苏州纳米技术与纳米仿生研究所 | 2022-02-18 | — | — | CN | disclosed |
| WO-2019173633-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INSULIN RESISTANCE | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2019-09-12 | — | — | WO | disclosed |
| WO-2019173640-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INSULIN RESISTANCE | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2019-09-12 | — | — | WO | disclosed |
| CN-110139644-A | For treating the composition and method of insulin resistance | 坦普尔大学 | 2019-08-16 | — | — | CN | disclosed |
| US-20190192462-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INSULIN RESISTANCE | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2019-06-27 | — | — | US | disclosed |
| CN-107974280-A | A kind of liquid acid alkylation reaction method | 中国石油化工股份有限公司 | 2018-05-01 | — | — | CN | disclosed |
| CN-103045156-A | Carbon nanotube in situ reinforced LED packaging silica gel and preparation method thereof | HANGZHOU ZFC NEW MATERIALS TECHNOLOGY CO LTD | 2013-04-17 | — | — | CN | disclosed |
| CN-1953747-A | Diphenyl-indol-2-on compounds and their use in the treatment of cancer | TOPOTARGET AS (DK) | 2007-04-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11596615-B2 | Compositions and methods for treatment of insulin resistance | GPR119, INSR, IAPP | CA5A 1758/4885CA5B 1677/4885ALDH1A1 2926/4885 |
| US-20190192462-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INSULIN RESISTANCE | GPR119, INSR, IAPP | CA5A 1758/4885CA5B 1677/4885ALDH1A1 2926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.