Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PARL | Q9H300 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1616337 | 0.68 | ALDH1A1 (0.42) | PARLNPSR1POLBL3MBTL1PKM | |
| SCHEMBL12569759 | 0.67 | PKM (0.60) | GAAPARLNPSR1POLBL3MBTL1 | |
| SCHEMBL10466729 | 0.65 | BRD4 (0.47) | GAAPARLPOLBL3MBTL1HTR6 | |
| SCHEMBL4825070 | 0.64 | CA1 (0.55) | GAANPSR1POLBL3MBTL1PKM | |
| SCHEMBL442392 | 0.64 | HTR6 (0.50) | PARLL3MBTL1PKMHTR6CYP2C9 | |
| SCHEMBL28657726 | 0.63 | ALDH1A1 (0.44) | PARLPOLBL3MBTL1HTR6CYP3A4 | |
| SCHEMBL11628895 | 0.63 | GAA (0.86) | GAAPOLBPKMLMNAALDH1A1 | |
| SCHEMBL6985985 | 0.62 | CYP2C9 (0.43) | PARLNPSR1POLBL3MBTL1PKM | |
| SCHEMBL2741400 | 0.62 | POLB (0.58) | GAAPOLBL3MBTL1PKMCYP2C9 | |
| (Phenylsulfonyl)Benzene SCHEMBL6912665 | 0.61 | HTR6 (0.74) | GAAPOLBL3MBTL1HTR6CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030181496-A1 | Pyrrole derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2003-09-25 | — | — | US | disclosed |
| EP-1310485-A1 | PYRROLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2003-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181496-A1 | Pyrrole derivatives | NCOA1, PKD1, NR3C2 | GAA 4826/4885PARL 4392/4885NPSR1 2172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.