Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.57 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12330052 | 0.83 | PKM (0.66) | POLBGAAALDH1A1HTTMEN1 | |
| SCHEMBL2694482 | 0.81 | MEN1 (0.76) | POLBALDH1A1CYP2C9MEN1KMT2A | |
| SCHEMBL3830424 | 0.78 | POLB (0.80) | POLBGAAALDH1A1CYP2C9PKM | |
| SCHEMBL735657 | 0.78 | POLB (0.80) | POLBGAAALDH1A1CYP2C9PKM | |
| SCHEMBL7122592 | 0.78 | POLB (0.80) | POLBGAAALDH1A1CYP2C9PKM | |
| SCHEMBL23564493 | 0.77 | PKM (0.53) | POLBGAAALDH1A1MAPTHTT | |
| SCHEMBL11628895 | 0.76 | GAA (0.86) | POLBGAAALDH1A1HTTMEN1 | |
| SCHEMBL5708819 | 0.75 | GAA (0.62) | POLBGAAALDH1A1HTTMEN1 | |
| SCHEMBL20599625 | 0.74 | CYP2C9 (0.61) | POLBGAAALDH1A1CYP2C9MEN1 | |
| SCHEMBL1988224 | 0.74 | ALDH1A1 (0.81) | POLBGAAALDH1A1CYP2C9PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160243535-A1 | CATALYST COMPLEX WITH CARBENE LIGAND | MATERIA, INC. | 2016-08-25 | — | — | US | disclosed |
| US-20160243535-A1 | CATALYST COMPLEX WITH CARBENE LIGAND | MATERIA, INC. | 2016-08-25 | — | — | US | disclosed |
| US-9339805-B2 | Catalyst complex with carbene ligand | MATERIA, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-9339805-B2 | Catalyst complex with carbene ligand | MATERIA, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-9233365-B2 | Catalyst complex with carbene ligand | MATERIA, INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-9233365-B2 | Catalyst complex with carbene ligand | MATERIA, INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-20150202610-A1 | CATALYST COMPLEX WITH CARBENE LIGAND | MATERIA, INC. (US) | 2015-07-23 | — | — | US | disclosed |
| US-20150202610-A1 | CATALYST COMPLEX WITH CARBENE LIGAND | MATERIA, INC. (US) | 2015-07-23 | — | — | US | disclosed |
| US-8859779-B2 | Catalyst complex with carbene ligand | MATERIA, INC. (US) | 2014-10-14 | — | — | US | disclosed |
| US-8859779-B2 | Catalyst complex with carbene ligand | MATERIA, INC. (US) | 2014-10-14 | — | — | US | disclosed |
| US-20130261296-A1 | CATALYST COMPLEX WITH CARBENE LIGAND | MATERIA, INC. | 2013-10-03 | — | — | US | disclosed |
| US-20130261296-A1 | CATALYST COMPLEX WITH CARBENE LIGAND | MATERIA, INC. | 2013-10-03 | — | — | US | disclosed |
| US-20120004418-A1 | Catalyst Complex With Carbene Ligand | MATERIA, INC. | 2012-01-05 | — | — | US | disclosed |
| US-20120004418-A1 | Catalyst Complex With Carbene Ligand | MATERIA, INC. | 2012-01-05 | — | — | US | disclosed |
| US-7902389-B2 | Catalyst complex with carbene ligand | MATERIA, INC. | 2011-03-08 | — | — | US | disclosed |
| US-20100160642-A1 | Catalyst Complex With Carbene Ligand | UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| US-7622590-B1 | Including a metal atom having anionic ligands, at least one nucleophilic carbene ligand, and an alkylidene, vinylidene, or allenylidene ligand; complexes are highly stable to air, moisture and thermal degradation; designed to efficiently carry out a variety of olefin metathesis reactions | UNIVERSITY OF NEW ORLEANS FOUNDATION (US) | 2009-11-24 | — | — | US | disclosed |
| US-7622590-B1 | Including a metal atom having anionic ligands, at least one nucleophilic carbene ligand, and an alkylidene, vinylidene, or allenylidene ligand; complexes are highly stable to air, moisture and thermal degradation; designed to efficiently carry out a variety of olefin metathesis reactions | UNIVERSITY OF NEW ORLEANS FOUNDATION (US) | 2009-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004418-A1 | Catalyst Complex With Carbene Ligand | ZC3H18, ZC3HAV1L, PDCD1LG2 | POLB 1027/4885GAA 3567/4885ALDH1A1 3385/4885 |
| US-20130261296-A1 | CATALYST COMPLEX WITH CARBENE LIGAND | ZC3HAV1L, PDCD1LG2, ICOSLG | POLB 919/4885GAA 3511/4885ALDH1A1 3335/4885 |
| US-20150202610-A1 | CATALYST COMPLEX WITH CARBENE LIGAND | ZC3HAV1L, PDCD1LG2, ICOSLG | POLB 919/4885GAA 3511/4885ALDH1A1 3335/4885 |
| US-20100160642-A1 | Catalyst Complex With Carbene Ligand | ZC3H18, ZC3HAV1L, PDCD1LG2 | POLB 1027/4885GAA 3567/4885ALDH1A1 3385/4885 |
| US-20160243535-A1 | CATALYST COMPLEX WITH CARBENE LIGAND | ZC3HAV1L, PDCD1LG2, ICOSLG | POLB 919/4885GAA 3511/4885ALDH1A1 3335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.