Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 10/20 | 0.47 |
| ▸ | NPC1 | O15118 | 9/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979336 | 0.85 | PDPK1 (0.50) | ACP1DYRK1AMAOBSMN1; SMN2LMNA | |
| SCHEMBL6983145 | 0.84 | DYRK1A (0.49) | ACP1DYRK1AMAOBRAB9ANPC1 | |
| SCHEMBL6981089 | 0.83 | MAPT (0.56) | DYRK1AMAOBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6975865 | 0.83 | TP53 (0.51) | ACP1DYRK1AMAOBRAB9ANPC1 | |
| SCHEMBL6975976 | 0.81 | ACP1 (0.47) | ACP1DYRK1AMAOBRAB9ANPC1 | |
| SCHEMBL6978201 | 0.80 | RAB9A (0.60) | MAOBRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL2210476 | 0.76 | DYRK1A (0.56) | ACP1DYRK1AMAOBRAB9ANPC1 | |
| SCHEMBL6980043 | 0.76 | DYRK1A (0.60) | ACP1DYRK1AMAOBRAB9ANPC1 | |
| SCHEMBL11224458 | 0.75 | DYRK1A (0.55) | ACP1DYRK1AMAOBRAB9ANPC1 | |
| SCHEMBL3093869 | 0.75 | RAB9A (0.57) | ACP1DYRK1AMAOBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006114-B1 | PYRAZOLE DERIVATIVES AND COX INHIBITORS CONTAINING THEM | GRELAN PHARMACEUTICAL CO (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-6136831-A | ANTIINFLAMMATORY AGENTS, GASTROINTESTINAL AGENTS, ENZYME INHIBITORS | GRELAN PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-1006114-A1 | PYRAZOLE DERIVATIVES AND COX INHIBITORS CONTAINING THEM | Grelan Pharmaceutical Co., Ltd. (JP) | 2000-06-07 | — | — | EP | disclosed |