Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978188 | 0.92 | LMNA (0.54) | ADRB2ADRB1ADRB3ALDH1A1LMNA | |
| SCHEMBL6981264 | 0.90 | NR3C1 (0.48) | ADRB2ADRB1ADRB3ALDH1A1LMNA | |
| SCHEMBL6985427 | 0.89 | NR3C1 (0.49) | ALDH1A1LMNAHPGDNPSR1NR3C1 | |
| SCHEMBL6984846 | 0.83 | USP2 (0.38) | ADRB2ADRB1ADRB3ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7409665 | 0.82 | NR3C1 (0.54) | ADRB2ADRB1ADRB3LMNANR3C1 | |
| SCHEMBL6984049 | 0.82 | NR3C1 (0.52) | ADRB2ADRB1ADRB3ALDH1A1LMNA | |
| SCHEMBL6981560 | 0.81 | PDK1 (0.37) | ADRB2ADRB1ADRB3ALDH1A1LMNA | |
| SCHEMBL6976718 | 0.80 | NR3C1 (0.42) | ALDH1A1LMNAHPGDNPSR1NR3C1 | |
| SCHEMBL6982740 | 0.78 | NR3C1 (0.59) | LMNANR3C1MAPTSMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL6985312 | 0.78 | NR3C1 (0.47) | ADRB2ADRB1ADRB3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |