Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | MASP2 | O00187 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948116 | 0.85 | TGFBR1 (0.32) | CTSCTGFBR1P2RX3MGLL | |
| SCHEMBL6982201 | 0.85 | TGFBR1 (0.33) | CTSCTGFBR1P2RX3 | |
| SCHEMBL6986001 | 0.84 | MASP2 (0.32) | CTSCTGFBR1MASP2P2RX3 | |
| SCHEMBL6987789 | 0.84 | CTSC (0.31) | CTSCTGFBR1 | |
| SCHEMBL6988069 | 0.83 | MASP2 (0.32) | CTSCTGFBR1MASP2P2RX3 | |
| SCHEMBL6983333 | 0.82 | TGFBR1 (0.33) | CTSCTGFBR1P2RX3 | |
| SCHEMBL6987478 | 0.81 | TGFBR1 (0.31) | CTSCTGFBR1 | |
| SCHEMBL6982377 | 0.80 | TGFBR1 (0.31) | CTSCTGFBR1 | |
| SCHEMBL7933428 | 0.78 | P2RX3 (0.33) | CTSCTGFBR1P2RX3MGLL | |
| SCHEMBL6987279 | 0.77 | CTSC (0.32) | CTSCTGFBR1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089964-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-10-29 | — | — | EP | disclosed |
| EP-1089964-A1 | HYDRAZINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2001-04-11 | — | — | EP | disclosed |
| WO-2000000465-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-01-06 | — | — | WO | disclosed |